Evidence is growing on the effectiveness of integrating safe water, hygiene, and sanitation interventions into HIV/AIDS programs, but little specific programming guidance exists. This document expands on an earlier August 2006 version with concrete guidance for implementers of HIV/AIDS care and support activities. USAID/HIP and the World Bank Water and Sanitation Program developed these recommendations through extensive consultations with HIV/AIDS and water sector researchers and program implementers and a broad review of the literature from different sectors.